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Matt Wolf has been lead trial counsel in some of the most significant cases brought by and against global technology companies. His professional activities focus on patent, trade secret, licensing, antitrust, and business tort issues, particularly involving life sciences technologies and computer hardware, software, and networking. While much of his practice is in federal trial courts throughout the United States, he also has extensive arbitration, appellate, and counseling/diligence experience.

Matt has been named both a Winning Litigator and Trailblazer by The National Law Journal. He has been recognized as a "key individual" for his achievements in patent litigation in Chambers USA. In 2022, he was named “IP Litigator of the Year” East Coast by Benchmark Litigation. He also is top ranked by IAM's Patent Litigation 1000: The World's Leading Patent Litigators, which has noted that he is a "trial supremo;" a "smart guy who knows how to frame the best case," with "tremendous trial skills and a superb ability to think on his feet," and "his cross-examination skills are some of the best." Prior to attending the University of Virginia School of Law, he was World University Debate Champion in 1990.


  • Hologic v. Minerva. As lead trial, appellate, and Supreme Court counsel in patent litigation, secured complete plaintiff and counter-claim defense jury verdict for Hologic, affirmance on appeal, and U.S. Supreme Court upholding of assignor estoppel doctrine. The SCOTUS decision has important implications for patent assignments, employee mobility, and due diligence of corporate transactions.
  • Boston Scientific v. Cook Group. Secured a US$158 million jury verdict and a finding of willful infringement as to all asserted patent claims in a suit between competitors in the endoscopy space. 
  • In re: Mallinckrodt PLC et al. Obtained complete defense verdict in bet-the-company trial, defeating antitrust and civil RICO claims against Mallinckrodt’s leading pharmaceutical, Acthar.
  • Amgen v. Sanofi/Regeneron. Successfully invalidated Amgen's patents in jury trial, and subsequently secured affirmance by the Federal Circuit, preserving Sanofi and Regeneron's ability to continue to market its life-saving cholesterol-reducing drug Praluent.
  • Hologic v. Fujifilm. Secured a complete win and limited exclusion order in the ITC in investigation of a four patent infringement complaint involving mammography imaging technology.
  • Boston Scientific v. Edwards Lifesciences Corp. Obtained jury verdict for Boston Scientific worth US$100 million+ in a patent litigation matter involving transcatheter aortic valves, while also obtaining a complete defense verdict on asserted patent counterclaims.
  • Heraeus v. Esschem/Zimmer Biomet. In asserting and defending claims of trade secret misappropriation of orthopedic product technology in the ITC and related district court and 3rd Cir. proceedings, secured complete defense victories and established misappropriation of trade secrets by opposing party.
  • BioMerieux v. Hologic/Grifols. Secured a complete jury verdict in defending against a US$100 million patent claim involving HIV-1 detection technology.
  • Drug-Coated Stent Wars. In a series of multibillion dollar, multijurisdictional disputes over market leading drug-coated stents, secured total victory for Boston Scientific: (1) JNJ/Wyeth v. Boston Scientific—in case related to drug carriers, invalidated all four patents-in-suit; (2) JNJ/Wyeth v. Boston Scientific—in case involving anti-proliferative drug, invalidated both patents-in-suit; and (3) JNJ v. Boston Scientific—in case involving stent architecture, secured non-infringement judgment.
  • Jang v. Boston Scientific. Obtained jury verdict defeating license breach and infringement claims for US$200 million in medical device dispute.
  • RGIS v. WIS. In litigation between primary competitors in retail audit space, secured invalidation of all hardware and software claims in district court and CBM proceedings.
  • Hologic v. IZI. Obtained infringement verdict and subsequent permanent injunction in suit involving accessories for mammography units.
  • Enzo v. GE/Amersham. Summary judgment in a decade-long biotech patent and licensing dispute.
  • Inflow v. Boston Scientific Corp. Won complete defense victory against an infringement claim for US$105 million involving medical device architecture patents.
  • Freedom Wireless, Inc. v. Verizon Wireless. Represented only victorious defendant in multi-defendant suit involving patents on telecommunications systems and equipment.
  • Boston Scientific v. Cook/Guidant. Secured permanent injunction valued at US$5 billion precluding early entry into drug eluting stent market.
  • Boston Scientific v. Medtronic. Won judgment in excess of US$160 million and secured injunction against future infringing sales of catheter systems.
  • Judicial Comment. Hon T. John Ward (ED Tex.) to the jury in Medtronic v. Boston Scientific (opposing counsel McKool Smith): "You've had an unusual experience in my nine years on the bench. I have never seen a case better tried by either side. So, the lawyers are to be complimented for the way they conducted themselves."
  • Judicial Comment. Hon. Ronald M. Whyte (ND Cal.) to parties in Hologic v. SenoRx (opposing counsel Williams & Connolly): "I've tried a number of patent cases and this was a real pleasure. I thought this was the most professionally handled case from both sides that I've seen and it sure made it a lot easier for me, and I appreciate it."


Chambers USA
Intellectual Property: Litigation — Washington, D.C. (2011-2023)
Life Sciences: IP/Patent Litigation — Nationwide (2023)
Chambers Global
Life Sciences: IP/Patent Litigation — USA (2023-2024)
Intellectual Property: Patent — USA (2021-2023)
Benchmark Litigation
Litigation Star — Intellectual Property (2024)
Top 100 Trial Lawyers — Intellectual Property (2024)
Intellectual Property Litigator of the Year — East Coast (2022)



  • J.D., University of Virginia School of Law, 1994
  • B.A., Political Science, Yale University, 1990


  • District of Columbia
  • Maryland
  • U.S. Court of Appeals for the Federal Circuit
  • U.S. Court of Appeals for the First Circuit
  • U.S. Court of Appeals for the Fourth Circuit
  • U.S. District Court, District of Maryland
  • U.S. District Court, Eastern District of Texas
  • Supreme Court of the United States